Understanding form and function in vascular tumours

The past twenty-five years have heralded an unparalleled increase in understanding of cancer. At the same time, mathematical modelling has emerged as a natural tool for unravelling the complex processes that contribute to the initiation and progression of tumours, for testing hypotheses about experimental and clinical observations, and assisting with the development of new approaches for improving its treatment. In this talk I will reflect on how increased access to experimental data is stimulating the application of new theoretical approaches for studying tumour growth. I will focus on two case studies which illustrate how mathematical approaches can be used to characterise and quantify tumour vascular networks, and to understand how microstructural features of these networks affect tumour blood flow.